My Critics Are Wrong
Why using human embryonic stem cells for medical research is moral.

By Ronald Bailey, science correspondent, Reason
July 25, 2001 8:35 a.m.

 

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atrick Lee and Robert P. George in their criticism of my Reason online article, "Are Stem Cells Babies?," quite properly insist that dissecting a human being for spare parts is "grotesquely immoral." However, they are wrong when they claim that obtaining embryonic stem cells for medical treatments is such a case.

Lee and George argue that my claim that there is no morally significant difference between skin cells and human embryonic stem cells is fallacious on two grounds: First, that the different potentialities of skin cells and embryos makes them morally different, and second, that human embryos are already "persons."

Let's take the second argument first because if embryos are already human beings then the notion of "potentiality" as conferring any moral significance on them is simply irrelevant in the first place. We all agree that one cannot kill human beings for spare parts.

Lee and George maintain that "it will not do to say that human [embryos] are "not 'persons.' You and I are essentially human, physical organisms. That is, we do not have organisms; we are rational, animal organisms. Therefore, we — that is, the persons we are — come to be precisely when the animal-organisms we are come to be. The human person is a bodily entity — not a mere consciousness using a body — and so the human person comes to be a conception." Of course, we are physical organisms and of course our organisms began at conception. That life begins at conception is a truism — no conception, no life. But that truism cannot tell one the moral status of that life. The question is were we people when we were embryos? The answer is no. Why? Insights about how we define the end of human life shed considerable light on what constitutes the beginning of human life. We used to declare people dead when their hearts stopped beating, until new biomedical advances forced us to think more carefully about what we mean when we say someone is dead. We now know that a body (a physical organism) may still breathe, its heart beat, and its stomach digest, but the person whose body it was is well and truly "brain dead." Thus technological advance has focused our attention on the central fact that we exist only if our brains are still working. If our brain activity ceases — our thoughts, memories, emotions, and intentions cease — we have ceased to be.

Therefore, it is widely agreed that it is permissible to dissect "brain dead" bodies for their spare parts. In fact, donating one's organs via one's will is generally regarded as a moral act, worthy of great approbation. Like brain-dead bodies, embryos consisting of 100 or so cells have no minds, memories, or intentions. Indeed, they have no brains, nor even any nerve cells. Consequently, since we do define "persons" as the sort of entities that do have brains capable of sustaining a mind, embryos clearly don't qualify. Despite Lee and George's claim to the contrary, it will do to say that embryos are not "persons" in the commonly understood meaning of that word.

Ah, but they could qualify, if they were allowed to fulfill their potential, Lee and George argue in their first line of attack. "The potentiality possessed by each of our cells differs profoundly from the potentiality of the human embryo," they claim. They base their distinction on the notion that all a single cell embryo needs is the "right environment to develop to a mature stage of a human being." Lee and George go on to argue that a skin cell "needs more than the right environment to develop to a mature stage of a human being." Here, Lee and George are begging the question. They arbitrarily restrict their notion of the "right environment" to there being a womb into which an embryo can implant.

In fact, when one looks further into the biochemical details of human development, the "right environment" is actually human egg cytoplasm, e.g., the substances outside an egg's nucleus. Egg cytoplasm has factors that can turn on the DNA recipes derived from either a combination of gametes (fertilization) or from somatic cell nuclei like those from skin cells (cloning) and begin the process that could lead to the development of a human being. Given this "right environment" skin cells as well as embryos could become human beings.

But let's peer further into the future of likely biomedical progress. Many researchers including former director of the National Institutes of Health, Harold Varmus think one day that recourse to egg cytoplasm will no longer be necessary to turn on the DNA recipes for making a human being. Whatever the factors found in egg cytoplasm are for turning on DNA recipes will become known and researchers will be able to apply them directly to somatic cells. The "right environment" will no longer involve human eggs at all. One could imagine a set of off the shelf protein factors with directions reading: Apply to skin cell; implant in womb; and wait nine months. Or in the alternative, apply to skin cell, wait seven days, derive stem cells, cure patient.

Another thought experiment helps illuminate the question of whether embryos are people or not. Imagine a skin cell whose DNA switches are being flipped one at a time in the proper order so that it is being taken back to the embryonic state. There is now only one more methyl group to remove from its DNA strands and the cell will be able to begin embryonic development. Does that cell's status as a person depend on the presence or absence of that one bit of methylation?

Scientific and technological developments like cloning shift our view from thinking of a single cell embryo as being "profoundly different" to being merely further along a newly accessible sequence of potentiality than are somatic cells. What once seemed like an unbreachable natural barrier has fallen and that changes our understanding of the world. Which then brings me back to Australian bioethicist Julian Savulsecu's conclusion that "If all our cells could be persons, then we cannot appeal to the fact that an embryo could be a person to justify the special treatment we give it."

I don't claim to know precisely when human life begins, but it certainly begins well after the blastocyst stage of embryonic development. Therefore I conclude that creating and using human embryonic stem cells to treat sick people is not immoral.

Finally, I want readers to keep in mind that the above discussion is not intended to nor does it address the politics surrounding the desirability of federal funding for human-embryonic-stem-cell research. Nor does it weigh the medical merits of adult-stem-cell research versus embryonic-stem-cell research. I simply answer in secular terms the question of whether research on human embryonic stem cells is moral or not. I know full well whom those readers who accept that God through his anointed representatives has told them that embryos are babies will believe. At the risk of being presumptuous, I still hope that the light that science sheds on this issue will lead faith communities to come to a different understanding one day. In the meantime, I hope that other readers not so persuaded by their faith will find my arguments enlightening and useful.

 
 

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