There are two ways to respond to extreme provocation.
1. John Randolph of Roanoke’s apocryphal response to an insinuation that he was not manly (Randolph’s voice never broke, and he never shaved): “You pride yourself on a faculty in which your slave is your equal, and your ass is your superior.”
2. Talleyrand’s response to a half hour long tantrum from Napoleon, who threw everything including Talleyrand’s lameness and cuckoldry at him: Talleyrand said not a word, and only remarked to someone else as he limped off, “It is a pity that a great man should be so ill bred.”
Either 1) go nuclear or 2) stay silently superior. The F-word fills neither bill.