Dear JohnD: The detail I remember from his tragigrotesque life (can’t remember where I read it) is that he had a horrible reaction to cold weather. One day he was out selling dictionaries door to door in Providence, RI when the temperature flukishly dropped . His wife had to go looking for him, and found him shivering and helpless on some street.
The aliens who interbred with the Lovecrafts must have been from one of those warm planets.