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Study: Ivermectin ‘Exhibits Efficacy’ as Therapeutic for COVID

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I stay out of the media wars about which therapeutics for COVID work, which don’t, and which are quackery. If it ever comes to having a personal stake in that question, I will trust my doctor.

But I couldn’t help notice the screeching media hysteria about people supposedly taking a horse deworming medicine called Ivermectin — without mentioning it has a human version — and the false stories of ERs so stuffed by people suffering adverse side effects from the veterinarian medication that other patients couldn’t be treated. The inexcusable baloney was launched by Rolling Stone and amplified by the usual left-wing suspects, such as MSNBC’s Rachel Maddow.

Well, a recently published study found that ivermectin exhibits efficacy against COVID! That’s the clear import of the title: “Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19.” Look at the findings, as stated in the paper’s abstract:

In 2015, the Nobel Committee for Physiology or Medicine, in its only award for treatments of infectious diseases since six decades prior, honoured the discovery of ivermectin (IVM), a multifaceted drug deployed against some of the world’s most devastating tropical diseases. Since March 2020, when IVM was first used against a new global scourge, COVID-19, more than 20 randomized clinical trials (RCTs) have tracked such inpatient and outpatient treatments.

Six of seven meta-analyses of IVM treatment RCTs reporting in 2021 found notable reductions in COVID-19 fatalities, with a mean 31% relative risk of mortality vs. controls. During mass IVM treatments in Peru, excess deaths fell by a mean of 74% over 30 days in its ten states with the most extensive treatments. Reductions in deaths correlated with the extent of IVM distributions in all 25 states with p < 0.002. Sharp reductions in morbidity using IVM were also observed in two animal models, of SARS-CoV-2 and a related betacoronavirus. The indicated biological mechanism of IVM, competitive binding with SARS-CoV-2 spike protein, is likely non-epitope specific, possibly yielding full efficacy against emerging viral mutant strains. [Emphasis added.]

And consider the conclusion:

We believe that the evidence to date supports the worldwide extension of IVM treatments for COVID-19, complementary to immunizations. The indicated biological mechanism of IVM, competitive binding with SARS-CoV-2 spike protein, is likely non-epitope specific, as reviewed [, possibly yielding full efficacy against emerging viral mutant strains.

IVM has been safely used in 3.7 billion doses since 1987, well tolerated even at much greater than standard doses and used without serious AEs in the three high-dose COVID-19 treatment studies noted above. In the current international emergency of COVID-19, with mutant viral strains, vaccination refusals and potentially waning immunities over months presenting new challenges, IVM can be an effective component of the mix of therapeutics deployed against this pandemic. [Emphasis added.]

People should only take strong medicines if prescribed by their doctors, of course, but good grief!

What a debacle for journalism. From now on, maybe the usual media suspects will think twice before slamming medicines because they think the story (or rumor they heard) somehow shames “the deplorables” they so despise.

Ha, Wesley! Who are you kidding? This episode was about fighting the culture war, not reporting about the epidemic.

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