Murkowski will vote “no” on preliminary procedural votes but “yes” on confirmation.
Collins has already stated she will not vote in favor of Barrett's nomination because of the vote's proximity to the presidential election.
Mitch McConnell has been warning his colleagues they need to be healthy and present for Senate votes.
Another lengthy and brutal Senate confirmation battle could hurt the Democratic electoral prospects in November.
"We can slow it down perhaps a matter of hours, maybe days at the most,” the number two Democrat in the Senate said.
The big question is, Can they get it done before Election Day?
Murkowski did emphasize that she opposed the confirmation process occurring fast and close to the election.
"These ugly smears against Judge Barrett are a combination of anti-Catholic bigotry and QAnon-level stupidity," Sasse commented in a statement.
Justice Ruth Bader Ginsburg’s recent health problems have revealed a rift among Senate Republicans over what to do if a Supreme Court seat becomes vacant.
Republican members of Congress remain divided on reforming qualified immunity, even as a GOP senator has proposed a bill that curbs protections officers currently enjoy.