I keep bringing stories like this up because the animal rights movementโs propaganda has seriously eroded the publicโs support for animal researchโnot to the point that a majority oppose itโbut the numbers should be limited to strict animal rightists, and itโs not. In any event, using genetically altered mice, scientists think they have found the cause of aging. From the story:
The Newcastle team, working with the University of Ulm in Germany, used a comprehensive โsystems biologyโ approach, involving computer modelling and experiments with cell cultures and genetically modified mice, to investigate why cells become senescent. In this aged state, cells stop dividing and the tissues they make up show physical signs of deterioration, from wrinkling skin to a failing heart.
The research, published by the journal Molecular Systems Biology, shows that when an ageing cell detects serious damage to its DNA โ caused by the wear and tear of life โ it sends out specific internal signals. These distress signals trigger the cellโs mitochondria, its tiny energy-producing power packs, to make oxidising โfree radicalโ molecules, which in turn tell the cell either to destroy itself or to stop dividing. The aim is to avoid the damaged DNA that causes cancer.
Huh, I thought this stuff never had an โaim.โ But I digress. It seems from this story that aging is a by product of a fail safe process by which cells destroy themselves in order to prevent cancer, and eventually the โcureโ produces the same result as the avoided diseaseโonly much later.
Without animal research as part of the usual integrated scientific approach, this potentially crucial information just could not have been found, nor the beneficial medical products likely to flow from this basic life science discovery, ever developed.
Oh, and for you transhumanists that think this will lead to your living foreverโsorry:
The answer is complex, and will not produce an elixir of eternal life in the foreseeable future.
But it could lead to better treatments to make our mortal lives more healthy and vigorous. Hurray.






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