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Addressing whether anything new in the Clinton e-mail scandal could end up being a game-changer, Charles Krauthammer pointed to the deleted e-mails as being connected with the Clinton Foundation in a damaging way:

Look, for a year I have thought, and I have said that I think the real hidden story in the e-mails — the reason she probably set it up in the first place, the reason it was all concealed, the reason so many were deleted, probably has to do with the foundation. And with the fact that it is inextricably bound with her tenure in the State Department and that, however — whether there is a smoking gun or not — there is a lot of smoke. Look at the numbers you showed: two thirds of Americans assume there was influence that was sold.
And the problem is that there are the 15,000. Look at what happened today; she gives a speech in Cincinnati, supposed to be a big speech. Foreign affairs, supposed to stake out her ground: completely ignored. The only story that you really hear about her is more of the e-mail story, the 15,000, all of this stuff. Every day the story is the e-mails. Every day is this story about her honesty. I think that’s the threat. That’s why her numbers have shrunk and that’s what she has to look ahead to for the next 70 days.