Jeremy Jacobs at Hotline writes:

The significance of the statement is, at least, two-fold. The first is the obvious: The Senate Majority Leader breaking with the president.
Secondly, Democrats had been remarkably disciplined in keeping silent on this issue. Until now. By speaking out and disagreeing with the president, Reid has virtually guaranteed that every Democratic senator will be asked about the mosque. That also guarantees that this story isn’t going anywhere.

Gosh, that must be exactly where the Democrats want to be less than a month out from the 9/11 anniversary.