While Mitch McConnell was unanimously chose to become the Republican Senate leader, the Democrats felt the reverberations of a wave election for the GOP. Harry Reid retained his role as leader of Senate Democrats, but four members of his caucus voted to go a different direction.

On Thursday, Louisiana’s Mary Landrieu, Missouri’s Claire McCaskill, North Dakota’s Heidi Heitkamp, and West Virginia’s Joe Manchin – all from red-leaning states – voted in opposition to Reid’s staying on as the party’s leader in the new Congress next year. Earlier in the day, McCaskill told reporters she would not back Reid, and Manchin hinted that he wanted new leadership.

“I voted for a change,” Manchin told reporters after the vote, according to the Hill. “I didn’t get a change.”

Landrieu’s opposition comes as the senator is locked in a tough runoff next month to keep her seat against Republican Bill Cassidy and looks to appeal to her state’s more conservative voters. On Wednesday, she further distanced herself from Reid while calling for a vote on construction of the Keystone XL pipeline, and asserting her eagerness to work with McConnell and Republicans.